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Tag: amitriptyline

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks
Mary CantĂș 7 December 2025 1

Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks

Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and cardiac arrhythmias-especially in older adults. Safer alternatives exist.

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